In vivo SilenceMag™ is a rapid, simple and highly efficient method dedicated to transfect small RNA (siRNA, miRNA) into target cells/tissue in vivo. It combines magnetic nanoparticles and small RNA that will be retained after injection at the magnetically targeted site. This targeted delivery method minimizes systemic distribution, increases gene targeted inactivation and reduces toxicity. Furthermore, the magnetic forces enhance the uptake of magnetic nanoparticles by the target tissue, and thus improve the efficiency of silencing.

This allows decreasing the required process time of delivery to few minutes which is crucial for improvement of in vivo small RNA delivery. In vivo SilenceMag™ is designed to meet in vivo grade quality.

In vivo SilenceMag™ benefits:

• Increased silencing efficiency
• Targeted process (magnetically-driven)
• Reduction of the systemic dissemination of siRNA/miRNA during injection
• Reduction of the siRNA/miRNA doses
• Work under non permissive conditions (hypothermia, physiological flow conditions)
• Penetration of the siRNA/miRNA into tissues
• Minimized toxicity

Storage: +4°C

Shipping Conditions: Room temperature

• NB: This reagent needs to be used with a magnet

OZ Biosciences

OZ Biosciences成立于2003年，为全球科学界和制药业生产专用的转染、转导试剂。公司专注于DNA、RNA和蛋白质等生物分子的体外和体内应用交付技术。

自2003年以来，OZ Biosciences为全球科学界和制药行业创建，开发和生产专门用于转染和转导工具的创新分子递送系统。OZ Biosciences专注于体外和体内应用的生物分子（例如DNA，RNA和蛋白质）的输送技术。 

在过去的几年中，生命科学经历了技术革命。在基因组学，功能基因组学和蛋白质组学领域所取得的进展为更好地理解基本生物学过程和开发下一代药物创造了绝佳的机会。

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